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HIV disease–related drug reaction is an adverse drug reaction caused by drugs used for the treatment of HIV/AIDS. Image of common antiretroviral drugs to treat HIV infection [ 1 ] Drug reactions are a major cause of mortality and morbidity around the world.
At lowered levels, protease inhibitors may not be effective in people taking both drugs, which means the virus that causes HIV/AIDS won't be stopped from replicating and may become resistant to the protease inhibitor. Efavirenz also affects antifungal drugs, which are used for fungal infections such as urinary tract infections.
The successful treatment and management of HIV/AIDS is affected by a plethora of factors which ranges from successfully taking prescribed medications, preventing opportunistic infection, and food access etc. Food insecurity is a condition in which households lack access to adequate food because of limited money or other resources.
Fostemsavir may cause a serious condition called immune reconstitution syndrome, similar to other approved drugs for treatment of HIV-1 infection. [8] This condition can happen at the beginning of HIV-1 treatment when the immune system may get stronger and begin to fight infections that have been hidden in the body for a long time. [8]
Acquired immunodeficiency syndrome (AIDS) is defined as an HIV infection with either a CD4 + T cell count below 200 cells per μL or the occurrence of specific diseases associated with HIV infection. [32] In the absence of specific treatment, around half of people infected with HIV develop AIDS within ten years. [32]
Zalcitabine (2′-3′-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV/AIDS. It is used as part of a combination regimen.
[4] [8] [9] It is the first FDA-approved injectable, complete regimen for HIV-infected adults that is administered once a month. [4] [5] It is also approved for use in Canada. [1] In the European Union, the two medications are approved separately and have different brand names: Vocabria (for cabotegravir) and Rekambys (for rilpivirine). [10 ...
Immune reconstitution inflammatory syndrome (IRIS) is a condition seen in some cases of HIV/AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.