Search results
Results from the WOW.Com Content Network
Sertraline was invented and developed by scientists at Pfizer and approved for medical use in the United States in 1991. It is on the World Health Organization's List of Essential Medicines. [16] It is available as a generic medication. [10] In 2016, sertraline was the most commonly prescribed psychotropic medication in the United States. [17]
The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, generalized anxiety disorder, panic disorder, obsessive–compulsive disorder (OCD), eating disorders, chronic pain, and, in some cases, for posttraumatic stress disorder (PTSD).
US Dermatologic toxicity. [3] Brotizolam: 1989 UK Animal carcinogenicity. [3] Bromfenac: 1998 US Severe hepatitis and liver failure (requiring transplantation). [2] Bucetin: 1986 Germany Kidney damage [3] Buformin: 1978 Germany Metabolic toxicity. [3] Bunamiodyl: 1963 Canada, UK, US Nephropathy. [11] Butamben (Efocaine)(Butoforme) 1964 US
An earlier version of this story erroneously reported the number of alerts over fatalities linked to the antidepressant citalopram since 2014 was 216, and the number of fatal adverse reactions ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
It was first approved for medical use in the United States in 1985. [36] Bupropion was originally called by the generic name amfebutamone, before being renamed in 2000. [16] In 2022, it was the 21st most commonly prescribed medication in the United States, with more than 25 million prescriptions.
According to the US government classification of psychiatric medications, TCAs are "non-abusable" [64] and generally have low misuse potential. [65] Nonetheless, due to their atypical mechanism of action, amineptine and tianeptine (dopamine reuptake inhibition and μ-opioid receptor agonism, respectively) are the two TCAs with the highest ...
Sertraline is the second most potent inhibitor of 5-HT re-uptake which has two very interesting characteristics that distinguish it i.e. sertraline's (1) inhibiting effect on DAT and NET and (2) the binding to sigma-1 (σ 1) receptor in CNS. [18]