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Lidocaine is an antiarrhythmic medication of the class Ib type. [8] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [11] [8] When injected near nerves, the nerves cannot conduct signals to or from the brain. [9] Lidocaine was discovered in 1946 and went on sale in 1948. [12]
Drugs with an intermediate duration of action (enabling pulpal anaesthesia for roughly 60 minutes) include Articaine HCl 4% + epinephrin 1:100,000, Articaine HCl 4% + epinephrin 1:200,000, Lidocaine HCl 2% + epinephrine 1:50,000, Lidocaine HCl 2% + epinephrine 1:80,000; Lidocaine HCl 2% + epinephrine 1:100,000 and Prilocaine HCl 4% ...
Lidocaine/prilocaine is a eutectic mixture of equal quantities (by weight) of lidocaine and prilocaine. A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for Eutectic Mixture of Local Anesthetics ). [ 5 ]
It is used as a eutectic mixture with lidocaine, 50% w/w, as lidocaine/prilocaine. The mixture is an oil with a melting point of 18 °C (64 °F). A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for eutectic mixture of local anesthetics). [3]
Trimecaine has two main application fields. The first one is local anesthesia (topical, infiltrational, topical mucosal and inhalational, spinal and Bier's intravenous). It is used in concentrations 0.4 up to 4%, in some cases (e.g. in stomatology) in mixtures with adrenaline.
Orabloc (articaine hydrochloride 4% and epinephrine 1:100,000) As articaine hydrochloride 4% with epinephrine 1:200,000 (0,005 mg/ml) Ubistesin; Ultracaine DS; Septanest N; Astracaine; Orabloc (articaine hydrochloride 4% and epinephrine 1:200,000) In the USA: As articaine hydrochloride 4% with epinephrine 1:100,000 Septocaine with epinephrine 1 ...
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