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Lidocaine is an antiarrhythmic medication of the class Ib type. [8] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [11] [8] When injected near nerves, the nerves cannot conduct signals to or from the brain. [9] Lidocaine was discovered in 1946 and went on sale in 1948. [12]
The GI cocktail is a mixture of a viscous anesthetic, an antacid, and an anticholinergic. [1] [2] Common viscous anesthetics use are viscous lidocaine or xylocaine.Common antacids used are magnesium hydroxide, aluminum hydroxide, or simethicone (more commonly known as Mylanta or Maalox). [3]
Topical anaesthetics in dentistry act on the peripheral nerves on mucosal surfaces to reduce sensation. Topical anaesthetics will contain either lidocaine or benzocaine as their active ingredient and come in a variety of forms, including solutions, creams, gels, and sprays. Indications for topical anaesthesia in dentistry includes:
It consists of a base solution of Plasma-lyte A, which has an electrolyte composition similar to that of extracellular fluid. To one liter of Plasma-lyte A, the following are added to make the crystalloid component of del Nido cardioplegia: Mannitol 20%, 16.3 mL; Magnesium sulfate 50%, 4 mL; Sodium bicarbonate 8.4%, 13 mL
Trimecaine has two main application fields. The first one is local anesthesia (topical, infiltrational, topical mucosal and inhalational, spinal and Bier's intravenous). It is used in concentrations 0.4 up to 4%, in some cases (e.g. in stomatology) in mixtures with adrenaline.
Lidocaine/prilocaine is a eutectic mixture of equal quantities (by weight) of lidocaine and prilocaine. A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for Eutectic Mixture of Local Anesthetics ). [ 5 ]
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