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Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
The FDA issued a statement on July 19, 2006, stating nursing mothers on SSRIs must discuss treatment with their physicians. However, the medical literature on the safety of SSRIs has determined that some SSRIs like Sertraline and Paroxetine are considered safe for breastfeeding. [148] [149] [150]
Breastfeeding may provide protection against postpartum depression or reduce some of its symptoms, [1] [4] [5] [3] and it is suggested that the benefits of breastfeeding may outweigh the benefits of antidepressants. [1] The abstinence of breastfeeding, or decreased breastfeeding can increase the mother's likelihood developing of this mental ...
Sertraline is the second most potent inhibitor of 5-HT re-uptake which has two very interesting characteristics that distinguish it i.e. sertraline's (1) inhibiting effect on DAT and NET and (2) the binding to sigma-1 (σ 1) receptor in CNS. [18]
Support - all NHS trusts should ensure there is a dedicated person to whom concerns can be easily reported and without formality, a "Freedom to Speak Up Guardian" . There are now over 800 Freedom to Speak Up Guardians in over 500 organisations in the NHS and independent sector organisations, national bodies and elsewhere in England.
Establishment of breastfeeding refers to the initiation of providing breast milk of mother to baby. According to the World Health Organization (WHO), [ 2 ] breastfeeding is the best way to provide nourishment, including essential nutrients , energy and antibodies , to infants and toddlers .
Serotonin. A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT).