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Trazodone, sold under many brand names, [1] is an antidepressant medication, [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
Severe gingivitis in dogs can further advance into periodontal disease in which the periodontal tissues begin to degrade and, if left untreated, can lead to tooth loss. [11] Studies have also shown that periodontal disease can negatively affect systemic health which impacts the overall health of the dog, therefore exhibiting the importance of ...
Very common (incidence > 10%) adverse effects include constipation, dry mouth, and drowsiness at the beginning of treatment. [5] [6]Common (1% < incidence ≤ 10%) adverse effects include drowsiness during maintenance therapy, tremor, headache, dizziness, vertigo, and weakness.
Artificial saliva is primarily used to relieve symptoms of xerostomia, known as dry mouth and hyposalivation, which is a condition that results in reduced saliva production. Various factors, including medication use, cancer therapy , and certain diseases, such as diabetes , stroke or Sjögren syndrome , can cause xerostomia. [ 1 ]
Xerostomia is the subjective sensation of dry mouth, which is often (but not always) associated with hypofunction of the salivary glands. [3] The term is derived from the Greek words ξηρός (xeros) meaning "dry" and στόμα (stoma) meaning "mouth". [4] [5] A drug or substance that increases the rate of salivary flow is termed a sialogogue.
The LD50 is when half the dogs die at that dose, so the toxic dose may be a lot lower, and if your dog has a health problem or is taking another medication, it may be even lower than that.
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