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Dose fractionation effects are utilised in the treatment of cancer with radiation therapy. When the total dose of radiation is divided into several, smaller doses over a period of several days, there are fewer toxic effects on healthy cells. This maximizes the effect of radiation on cancer and minimizes the negative side effects. A typical ...
To that end, the ICLDRR has assembled and analysed virtually all published data on cancer induction in laboratory animals by low doses of ionizing radiation, and published initial findings at specialized international conferences, since 1998. The foremost contribution of the ICLDRR is the setup of a radiation low-dose mammal-experiment database.
Many low-dose palliative treatments (for example, radiation therapy to bony metastases) cause minimal or no side effects, although short-term pain flare-up can be experienced in the days following treatment due to oedema compressing nerves in the treated area. Higher doses can cause varying side effects during treatment (acute side effects), in ...
A very low dose of a chemical agent may trigger from an organism the opposite response to a very high dose.. Radiation hormesis proposes that radiation exposure comparable to and just above the natural background level of radiation is not harmful but beneficial, while accepting that much higher levels of radiation are hazardous.
Curved cell survival curves (cells exposed to low-LET radiation) show two distinct regions: low dose regions and high dose regions. The low-dose region is often referred to as the “shoulder”, and in this region there are fewer cell inactivations per unit dose. The high-dose region generally trends towards a straight line. Two general ...
Increased Risk of Solid Cancer with Dose for A-bomb survivors, from BEIR report.Notably, this exposure pathway occurred from essentially a massive spike or pulse of radiation, a result of the brief instant that the bomb exploded, which while somewhat similar to the environment of a CT scan, is wholly unlike the low dose rate of living in a contaminated area such as Chernobyl, where the dose ...
Fast food gets a bad rap for being unhealthy, but there are healthy fast food options at chains like McDonald’s, Pizza Hut, and Sonic. Dietitians explain.
Adjustments for photon energy or dose-rate and fractionation have not been made. These types of analysis lend confidence to risk assessments as well as showing the limitations of such data sets. Of special interest to NASA is the dependence on age at exposure of low-LET cancer risk projections.