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Bacitracin is primarily used as a topical preparation, as it can cause kidney damage when used internally. [3] It is generally safe when used topically, but in rare cases may cause hypersensitivity , allergic or anaphylactic reactions, especially in people allergic to neomycin .
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]
Bacitracin is a polypeptide antibiotic derived from a bacterium, Bacillus subtilis, and acts against bacteria through the inhibition of cell wall synthesis. [6] It does this by inhibiting the removal of phosphate from lipid compounds, thus deactivating its function to transport peptidoglycan; the main component of bacterial cell membranes, to the microbial cell wall.
It is also available as the combinations bacitracin/polymyxin B and neomycin/polymyxin B/bacitracin for use on the skin. [3] [4] Common side effects when given by injection include kidney problems, neurological problems, fever, itchiness, and rash. [1] Injections into muscle may result in significant pain. [1]
Bacitracin/polymyxin B (trade name Polysporin among others) is a topical antibiotic cream or ointment. [1] The active ingredients are polymyxin B , bacitracin and occasionally garamycin or gramicidin .
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ATC code D06 Antibiotics and chemotherapeutics for dermatological use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
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3579 S High St, Columbus, OH · Directions · (614) 409-0683