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  2. Omeprazole - Wikipedia

    en.wikipedia.org/wiki/Omeprazole

    Omeprazole was a subject of a patent litigation in the U.S. [66] The invention involved application of two different coatings to a drug in pill form to ensure that the omeprazole did not disintegrate before reaching its intended site of action in stomach. Although the solution by means of two coating was obvious, the patent was found valid ...

  3. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    [20] [21] [22] In the United States, the Food and Drug Administration (FDA) has advised that over-the-counter PPIs, such as Prilosec OTC, should be used no more than three 14-day treatment courses over one year. [23] [24] Despite their extensive use, the quality of the evidence supporting their use in some of these conditions is variable.

  4. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]

  5. 5 Things to Avoid When You Have Alopecia Areata - AOL

    www.aol.com/5-things-avoid-alopecia-areata...

    The Food and Drug Administration (FDA) also recently approved Olumiant, a new treatment for severe alopecia areata. This medication is a Janus kinase (JAK) inhibitor that works by blocking the ...

  6. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.

  7. Mark Cuban: 'No one should have to choose between food ... - AOL

    www.aol.com/finance/mark-cuban-no-one-choose...

    The drug with the biggest savings through Cost Plus Drugs is Imatinib, a generic for Gleevec that’s used to treat leukemia. ... Other drugs with major savings include Omeprazole-Sodium ...

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