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2. RALES (trial) - Wikipedia

   en.wikipedia.org/wiki/RALES_(trial)

   The RALES trial established spironolactone as a vital component of therapy for patients with severe heart failure, demonstrating significant reductions in mortality and hospitalization and improvements in symptoms. The trial's findings have been instrumental in shaping current heart failure treatment guidelines and improving patient outcomes.

3. Management of heart failure - Wikipedia

   en.wikipedia.org/wiki/Management_of_heart_failure

   Sleep apnea is an under-recognized risk factor for heart failure. Uncontrolled sleep apnea may increase the risk of heart failure by up to 140%. [4] Weight reduction – through physical activity and dietary modification, as obesity is a risk factor for heart failure and left ventricular hypertrophy. Effective weight management has been shown ...

4. Mineralocorticoid receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/Mineralocorticoid_receptor...

   This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure. Spironolactone, the first member of the class, is also used in the management of hyperaldosteronism (including Conn's syndrome) and female hirsutism (due to additional antiandrogen actions).

5. Heart failure - Wikipedia

   en.wikipedia.org/wiki/Heart_failure

   N-terminal pro-BNP (NT-proBNP) is the favored biomarker for the diagnosis of heart failure, according to guidelines published 2018 by NICE in the UK. [3] Brain natriuretic peptide 32 (BNP) is another biomarker commonly tested for heart failure. [74] [6] [75] An elevated NT-proBNP or BNP is a specific test indicative of heart failure ...

6. Spironolactone - Wikipedia

   en.wikipedia.org/wiki/Spironolactone

   Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. [4] It is also used in the treatment of high blood pressure , and low blood potassium that does not improve with supplementation , early puberty in boys, acne ...

7. This Cardio Machine Gives You The Biggest Burn, According To ...

   www.aol.com/cardio-machine-gives-biggest-burn...

   A 2021 study found that the treadmill is the most effective cardio machine for weight loss. A trainer explains why—and reveals the best treadmill workouts.

8. Fantasy football Start 'Em, Sit 'Em: 40 players to start or ...

   www.aol.com/fantasy-football-start-em-sit...

   Week 12 marks the first "Byemageddon” of the NFL season in fantasy football. A season-high six teams have their bye this week: the New York Jets, Atlanta Falcons, Buffalo Bills, Cincinnati ...

9. Potassium-sparing diuretic - Wikipedia

   en.wikipedia.org/wiki/Potassium-sparing_diuretic

   They are typically used as an adjunct in management of hypertension, cirrhosis, and congestive heart failure. [3] The steroidal aldosterone antagonists can also be used for treatment of primary hyperaldosteronism. Spironolactone, a steroidal aldosterone antagonist, is also used in management of female hirsutism and acne from PCOS or other ...