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  2. Batten disease - Wikipedia

    en.wikipedia.org/wiki/Batten_disease

    Batten disease is a fatal disease of the nervous system that typically begins in childhood. [1] Onset of symptoms is usually between 5 and 10 years of age. [1] Often, it is autosomal recessive.

  3. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    As of 2012, the five-year survival rate for systemic scleroderma was about 85%, whereas the 10-year survival rate was just under 70%. [44] This varies according to the subtype; while localized scleroderma rarely results in death, the systemic form can, and the diffuse systemic form carries a worse prognosis than the limited form.

  4. Peripheral artery disease - Wikipedia

    en.wikipedia.org/wiki/Peripheral_artery_disease

    The incidence of symptomatic PAD increases with age, from about 0.3% per year for men aged 40–55 years to about 1% per year for men aged over 75 years. The prevalence of PAD varies considerably depending on how PAD is defined and the age of the population being studied.

  5. Sudden arrhythmic death syndrome - Wikipedia

    en.wikipedia.org/wiki/Sudden_arrhythmic_death...

    A 2011 retrospective cohort study using demographic and autopsy data for a 10-year period comprising 15.2 million person-years of active surveillance suggested that prevention of sudden death in young adults should focus on evaluation for causes known to be associated with SCD (e.g., primary arrhythmia) among those under 35 years old, and ...

  6. Chronic limb threatening ischemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_limb_threatening...

    Other factors which may point to a diagnosis of critical limb ischemia are a Buerger's angle of less than 20 degrees during Buerger's test, a capillary refill of more than 15 seconds or diminished or absent pulses. [citation needed] Critical limb ischemia is different from acute limb ischemia. Acute limb ischemia is a sudden lack of blood flow ...

  7. Subacute sclerosing panencephalitis - Wikipedia

    en.wikipedia.org/wiki/Subacute_sclerosing_pan...

    In the classic presentation of the disease, death occurs in 1 to 3 years, [15] but faster and slower progressions can occur. Faster deterioration in cases of acute fulminant SSPE leads to death within 3 months of diagnosis. [16] [17] Although the prognosis is bleak for SSPE past stage 1, there is a 5% spontaneous remission rate. This may take ...

  8. Postural orthostatic tachycardia syndrome - Wikipedia

    en.wikipedia.org/wiki/Postural_orthostatic...

    Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...

  9. Hypertensive emergency - Wikipedia

    en.wikipedia.org/wiki/Hypertensive_emergency

    Commonly, ischemic heart attack and stroke are the causes that lead to death in patients with severe hypertension. It is estimated that for every 20 mm Hg systolic or 10 mm Hg diastolic increase in blood pressures above 115/75 mm Hg, the mortality rate for both ischemic heart disease, cancer and stroke doubles. [citation needed]