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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.
Lupus can also affect the serosa, which is like the outer membrane of an organ or tissue, so if it gets inflamed, people get get serositis, which could manifest as something like pleuritis, which is inflammation of the lining around the lungs and chest cavity, or as pericarditis, inflammation of the lining of the heart.
In the new NHS trial, three patients have received the therapy for the most serious form of lupus, a condition that can be life-threatening and cause damage to the heart, lungs, brain and kidneys.
Rheumatic heart disease: Heart valves: Anti-streptolysin O (ASO), anti-DNase B Confirmed Declining due to improved treatment of strep throat [30] Kawasaki disease: Coronary arteries: Unknown Probable 20 per 100,000 children under age 5 [31] Giant cell arteritis: Large and medium arteries, can affect coronary arteries None specific Confirmed
Heart disease is a type of cardiovascular disease that affects the heart’s structure and function. ... such as scleroderma, lupus, and rheumatoid arthritis, may also contribute to pericarditis ...
Common symptoms include extreme fatigue, joint pain or skin rashes. In rare cases, the disease may lead to kidney or heart damage, or weaken the immune system so the body can’t fight off infections.
Unlike rheumatoid arthritis, lupus arthritis is less disabling and usually does not cause severe destruction of the joints. Fewer than ten percent of people with lupus arthritis will develop deformities of the hands and feet. [20] People with SLE are at particular risk of developing osteoarticular tuberculosis. [21]
T he 1.5 million Americans estimated to have the autoimmune disease lupus already have plenty to manage—what with the pain, fatigue, hair loss, and heart problems the condition can cause. So ...
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