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  2. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    Another estimation tool to calculate GFR is the Mayo Quadratic formula. This formula was developed by Rule et al., [32] in an attempt to better estimate GFR in patients with preserved kidney function. It is well recognized that the MDRD formula tends to underestimate GFR in patients with preserved kidney function.

  3. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    The above formula only applies for GFR calculation when it is equal to the clearance rate. The normal range of GFR, adjusted for body surface area, is 100–130 average 125 (mL/min)/(1.73 m 2) in men and 90–120 (mL/min)/(1.73 m 2) in women younger than the age of 40. In children, GFR measured by inulin clearance is 110 (mL/min)/(1.73 m 2 ...

  4. Filtration fraction - Wikipedia

    en.wikipedia.org/wiki/Filtration_fraction

    In renal physiology, the filtration fraction is the ratio of the glomerular filtration rate (GFR) over the renal plasma flow (RPF). Filtration Fraction, FF = GFR/RPF, or =. The filtration fraction, therefore, represents the proportion of the fluid reaching the kidneys that passes into the renal tubules. It is normally about 20%.

  5. Fractional excretion of sodium - Wikipedia

    en.wikipedia.org/wiki/Fractional_excretion_of_sodium

    This is the numerator in the equation. The denominator is the total amount of sodium filtered by the kidneys. This is calculated by multiplying the plasma sodium concentration by the glomerular filtration rate (GFR) calculated using creatinine filtration. The flow rates then cancel out, simplifying to the standard equation: [1]

  6. Renal clearance ratio - Wikipedia

    en.wikipedia.org/wiki/Renal_clearance_ratio

    Diagram showing the basic physiologic mechanisms of the kidney. The renal clearance ratio or fractional excretion is a relative measure of the speed at which a constituent of urine passes through the kidneys.

  7. Kidney failure - Wikipedia

    en.wikipedia.org/wiki/Kidney_failure

    Chronic kidney failure is measured in five stages, which are calculated using the person's GFR, or glomerular filtration rate. Stage 1 CKD is mildly diminished renal function, with few overt symptoms. Stages 2 and 3 need increasing levels of supportive care from their medical providers to slow and treat their renal dysfunction.

  8. Creatinine - Wikipedia

    en.wikipedia.org/wiki/Creatinine

    The IDMS method would result in comparative overestimation of the corresponding calculated GFR in some patients with normal renal function. A few medicines are dosed even in normal renal function using that derived value of GFR. The dose, unless further modified, could then be higher than desired, potentially causing increased drug-related ...

  9. Starling equation - Wikipedia

    en.wikipedia.org/wiki/Starling_equation

    Glomerular capillary is more familiarly known as the glomerular filtration rate (GFR). In the rest of the body's capillaries, J v {\displaystyle J_{v}} is typically 5 ml/ min (around 8 litres/ day), and the fluid is returned to the circulation via afferent and efferent lymphatics.