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Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxiety; the hippocampus, which plays an important role in memory formation; and some ...
Serotonin pathways are thought to modulate eating, both the amount as well as the motor processes associated with eating. The serotonergic projections into the hypothalamus are thought to be particularly relevant, and an increase in serotonergic signaling is thought to generally decrease food consumption (evidenced by fenfluramine , however ...
Examples are dopamine, norepinephrine and serotonin. All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, and tryptophan by the action of aromatic amino acid decarboxylase enzymes. They are deactivated in the body by the enzymes known as monoamine oxidases which clip off the amine group.
SSRIs, which first came onto the market in the 1980s, work by blocking the reabsorption of serotonin into your brain. This increases the levels of serotonin on hand and can lessen anxiety symptoms.
The function of the 5-HT1e receptor is unknown due to the lack of selective pharmacological tools, specific antibodies, and permissive animal models. [7] The 5-HT1e receptor gene lacks polymorphisms amongst humans (few mutations), indicating a high degree of evolutionary conservation of genetic sequence, which suggests that the 5-HT1e receptor has an important physiological role in humans. [8]
“A solid bedtime routine sets you up for quality sleep, which is essential for mental clarity, memory, and focus,” she states. “Good sleep allows the brain to process the day’s information ...
In the brain, said Becker, B6 “aids in the synthesis of neurotransmitters — e.g., serotonin, dopamine, gamma-aminobutyric acid — and helps reduce homocysteine levels in the blood.”