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Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
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These work best when combined with other healthy lifestyle choices, like eating a healthy diet and engaging in physical activity 8 Weight Loss Vitamins and Supplements to Boost Metabolism
On 23 January 2006, an FDA advisory panel voted 11 to 3 to recommend the approval of an OTC formulation of orlistat, to be sold under the brand name Alli by GlaxoSmithKline. [41] Approval was granted on 7 February 2007, [ 42 ] and Alli became the first weight loss drug officially sanctioned by the U.S. government for over-the-counter use. [ 43 ]
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