Search results
Results from the WOW.Com Content Network
Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases. Phenformin was developed in 1957 by Ungar, Freedman and Seymour Shapiro, working for the U.S. Vitamin Corporation ...
The signs and symptoms of acute beryllium pneumonitis usually resolve over several weeks to months, but may be fatal in 10 percent of cases, [1] and about 15–20% of cases may progress to chronic beryllium disease. [8] Acute beryllium poisoning approximately doubles the risk of lung cancer. [9]
The Common Terminology Criteria for Adverse Events (CTCAE), [1] formerly called the Common Toxicity Criteria (CTC or NCI-CTC), are a set of criteria for the standardized classification of adverse events of drugs and treatment used in cancer therapy. The CTCAE system is a product of the US National Cancer Institute (NCI).
“There are more than 200 types of cancer, with lots of possible symptoms,” says Dr Julie Sharp, head of health and patient information at CRUK. “It’s impossible to know them all, which is ...
Beryllium poisoning is poisoning by the toxic effects of beryllium, or more usually its compounds. It takes two forms: Acute beryllium poisoning, usually as a result of exposure to soluble beryllium salts; Chronic beryllium disease (CBD) or berylliosis, usually as a result of long-term exposure to beryllium oxide usually caused by inhalation.
Generally, different sets of experiments are conducted to determine whether a substance causes cancer and to examine other forms of toxicity. [16] Factors that influence chemical toxicity: [12] Dosage Both large single exposures (acute) and continuous small exposures (chronic) are studied. Route of exposure Ingestion, inhalation or skin absorption
Nausea and vomiting may have a number of causes in people with cancer. [7] While more than one cause may exist in the same person stimulating symptoms via more than one pathway, the actual cause of nausea and vomiting may be unknown in some people. The underlying causes of nausea and vomiting may in some cases not be directly related to the ...