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Critical limb ischemia is diagnosed by the presence of ischemic rest pain, and an ulcers that will not heal or gangrene due to insufficient blood flow. [3] Insufficient blood flow may be confirmed by ankle-brachial index (ABI), ankle pressure, toe-brachial index (TBI), toe systolic pressure, transcutaneous oxygen measurement (TcpO2 ), or skin perfusion pressure (SPP).
Peripheral artery disease most commonly affects the legs, but other arteries may also be involved, such as those of the arms, neck, or kidneys. [4] [17] Peripheral artery disease (PAD) is a form of peripheral vascular disease. Vascular refers to both the arteries and veins within the body. PAD differs from peripheral veinous disease. PAD means ...
Gangrene is a type of tissue death caused by a lack of blood supply. [4] Symptoms may include a change in skin color to red or black, numbness, swelling, pain, skin breakdown, and coolness. [1] The feet and hands are most commonly affected. [1] If the gangrene is caused by an infectious agent, it may present with a fever or sepsis. [1]
It also the most common cause of amputation in the US, usually toes and feet, often as a result of gangrene, and almost always as a result of peripheral artery disease. Retinal damage (from microangiopathy ) makes it the most common cause of blindness among non-elderly adults in the US.
Thromboangiitis obliterans, also known as Buerger disease (English / ˈ b ɜːr ɡ ər /; German: [ˈbʏʁɡɐ]) or Winiwarter-Buerger disease, is a recurring progressive inflammation and thrombosis (clotting) of small and medium arteries and veins of the hands and feet.
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The ulcer has punched-out appearance. It is intensely painful. It has gray or yellow fibrotic base and undermining skin margins. Pulses are not palpable. Associated skin changes may be observed, such as thin shiny skin and absence of hair.
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