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An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis, forming oogonia. During oogenesis, the oogonia become primary oocytes. An oocyte is a form of genetic material that can be collected for cryoconservation.
Oogenesis starts with the process of developing primary oocytes, which occurs via the transformation of oogonia into primary oocytes, a process called oocytogenesis. [11] From one single oogonium, only one mature oocyte will rise, with 3 other cells called polar bodies. Oocytogenesis is complete either before or shortly after birth.
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Male germ cells produced in the testicles can carry out special DNA repair processes that act during meiosis to repair DNA damages and to maintain the integrity of the genomes that are to be transmitted to progeny. [7] These DNA repair processes include homologous recombinational repair and non-homologous end joining. [7]
Oocytogenesis : third trimester primary Oocyte: diploid/46: 4C: Ootidogenesis (meiosis 1) (Folliculogenesis) -- polar body separated: Dictyate in prophase I until ovulation secondary Oocyte: haploid/23: 2C: Ootidogenesis (meiosis 2) -- polar body separated: Halted in metaphase II until fertilization Ootid: haploid/23: 1C: Maturation: Minutes ...
Diagrams to show the development of male and female generative organs from a common type. A.—Diagram of the primitive urogenital organs in the embryo previous to sexual distinction. 3. Ureter. 4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls.
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The zona pellucida is a translucent matrix of cross-linked glycoprotein filaments that surrounds the mammalian oocyte and is 6.5–20 μm thick depending on the species. Its formation, which depends on a conserved zona pellucida-like (ZP) module that mediates the polymerization of egg coat components, [2] is critical to successful fertilization. [3]