Search results
Results from the WOW.Com Content Network
While knowledge was being accumulated regarding the biology of phages and how to use phage cocktails correctly, early uses of phage therapy were often unreliable. [29] Since the early 20th century, research into the development of viable therapeutic antibiotics had also been underway, and by 1942, the antibiotic penicillin G had been ...
George Eliava pioneered the use of phages in treating bacterial infections. Phages were discovered to be antibacterial agents and were used in the former Soviet Republic of Georgia (pioneered there by Giorgi Eliava with help from the co-discoverer of bacteriophages, Félix d'Hérelle) during the 1920s and 1930s for treating bacterial infections.
Mycobacteriophage Bxb1 Structure [1]. A mycobacteriophage is a member of a group of bacteriophages known to have mycobacteria as host bacterial species. While originally isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis, [2] the causative agent of tuberculosis, more than 4,200 mycobacteriophage species have since been isolated from various environmental ...
Production problems were most likely due to the attempt to mass-produce phages when they were barely understood. The phages may have been damaged and/or too low in concentration. Another possibility is that incorrect diagnoses led to the use of the irrelevant types of phages that were not adapted to the host bacteria of interest. Many studies ...
Bacillus phage are classified based on their genome sequences. The total sequence length ranges from 7,826 (in phage pMC8) to 509,170 bp (in phage pHS181) with the GC content of these phage being an average of 38.25%. [6] Within Bacillus phage there are 12 clusters (A-L), 28 subclusters, and 14 singletons.
The report lists the quantities of PX used and the number of infected individuals in various locations in China, including Nong'an, Quzhou, Ningbo, Changde, Guangxin, Guangfeng and Yushan. It states that over 26,000 people were infected once or twice, defining PX as "the best bacterial bomb, capable of causing psychological and economic panic ...
Many of the leaders of the emerging field of molecular biology were alumni of the phage course, which continued to be taught through the 1950s and 1960s. [ 24 ] [ 25 ] In 1995, Millard Susman published a retrospective article on the phage course as it was given over the years (1945 – 1970) both at Cold Spring Harbor (New York) and at the ...
Phages make up the majority of most viromes and are currently understood as being the most abundant organism. [5] Oftentimes scientists will look only at a phageome instead of a virome while conducting research. Variations due to many factors have also been explored such as diet, age, and geography.