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A 2012 study suggests that players in the National Football League are three times more likely to die from neurodegenerative diseases, including Alzheimer's and Parkinson's diseases, than the general US population. [43] A 2018 study found 56% increase in risk of Parkinson's disease among US military veterans suffered traumatic brain injury. [42]
Cotinine is an alkaloid found in tobacco [1] and is also the predominant metabolite of nicotine, [2] [3] typically used as a biomarker for exposure to tobacco smoke. Cotinine is currently being studied as a treatment for depression, post-traumatic stress disorder (PTSD), schizophrenia, Alzheimer's disease and Parkinson's disease.
Parkinson's disease ... linked to Gaucher's disease, are found in 5–15 percent of PD cases. ... Reliable biomarkers are needed for early diagnosis, ...
Anavex Life Sciences Corp (NASDAQ: AVXL) has announced the presentation of Phase 2 clinical biomarker data from the ANAVEX2-73-PDD-001 Parkinson's Disease Dementia (PDD) study at the AD/PD 2022 ...
In 2023, a longitudinal study funded by the organization, the Parkinson's Progression Markers Initiative, released results in Lancet Neurology showing Parkinson's can be detected by the presence of a biomarker protein, abnormal alpha-synuclein. [4] [9] [10] [11] The biomarker can be detected before the onset of symptoms. [12]
Mutations in this gene have been associated with Parkinson's disease type 8. [20] [21] The G2019S mutation results in enhanced kinase activity, and is a relatively common cause of familial Parkinson's disease in Caucasians. [22] It may also cause sporadic Parkinson's disease. The mutated Gly amino acid is conserved in all kinase domains of all ...
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