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Thyrotoxic myopathy (TM) is a neuromuscular disorder that develops due to the overproduction of the thyroid hormone thyroxine.Also known as hyperthyroid myopathy, TM is one of many myopathies that lead to muscle weakness and muscle tissue breakdown.
Weakness or muscle weakness (especially in the large muscles of the arms and legs). This latter occurs in 60 to 80 percent of patients with untreated hyperthyroidism. [10] Muscle weakness is rarely the chief complaint.
The weakness is usually symmetrical; [5] the limb muscles closer to the trunk (proximal) are predominantly affected, and weakness tends to start in the legs and spread to the arms. Muscles of the mouth and throat , eyes , and breathing are usually not affected, but occasionally weakness of the respiratory muscles can cause life-threatening ...
Thyroid-associated ophthalmopathy (TAO), or thyroid eye disease (TED), is the most common extrathyroidal manifestation of Graves' disease. It is a form of idiopathic lymphocytic orbital inflammation , and although its pathogenesis is not completely understood, autoimmune activation of orbital fibroblasts , which in TAO express the TSH receptor ...
Overactive thyroid, hyperthyreosis: Triiodothyronine (T 3, pictured) and thyroxine (T 4) are both forms of thyroid hormone. Specialty: Endocrinology: Symptoms: Irritability, muscle weakness, sleeping problems, fast heartbeat, heat intolerance, diarrhea, enlargement of the thyroid, weight loss [1] Complications: Thyroid storm [2] Usual onset: 20 ...
Pain or cramping in your legs. High levels of LDL, cholesterol, or triglycerides can cause peripheral artery disease, in which the arteries that carry blood to your legs can narrow or become ...
[13] [10] Extended thyroid hormone deficiency may lead to muscle fibre changes, with fast-twitching type II being replaced by slow-twitching type-I fibers, resulting in muscle weakness, muscle pain, stiffness, and rarely, pseudohypertrophy. [17]
You might notice pain or cramps in your legs when you walk or exercise, and the pain may go away when you rest. Sudden weakness, slurred speech, visual disturbances, or stroke. Dyslipidemia can ...
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