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Whipple's disease is a rare systemic infectious disease caused by the bacterium Tropheryma whipplei.First described by George Hoyt Whipple in 1907 and commonly considered as a gastrointestinal disorder, Whipple's disease primarily causes malabsorption, but may affect any part of the human body, including the heart, brain, joints, skin, lungs and the eyes. [1]
Infected individuals who experience symptoms (about 10% have no symptoms) may have diarrhea, abdominal pain, and weight loss. [1] Less common symptoms include vomiting and blood in the stool. [1] Symptoms usually begin one to three weeks after exposure and, without treatment, may last two to six weeks or longer. [4]
The prodromal symptoms are fever, headache, and myalgia, which can be severe, lasting as long as 24 hours.After 1–5 days, typically, these are followed by diarrhea (as many as 10 watery, frequently bloody, bowel movements per day) or dysentery, cramps, abdominal pain, and fever as high as 40 °C (104 °F).
Antimotility medication has a theoretical risk of causing complications, and although clinical experience has shown this to be unlikely, [43] these drugs are discouraged in people with bloody diarrhea or diarrhea that is complicated by fever. [77] Loperamide, an opioid analogue, is commonly used for the symptomatic treatment of diarrhea. [78]
[2] [6] Newborns and infants may normally have soft and frequent stools; however, any noticeable changes in stool frequency or form (i.e. watery) can indicate toddler's diarrhea. [7] Other symptoms may include chills, fever, abdominal pain or cramping, nausea, and/or vomiting. [6] Undigested food and/or mucus may also be observed in stools. [8]
“Norovirus is the leading cause of vomiting and diarrhea from acute gastroenteritis in the U.S., responsible for 58% of foodborne illnesses and about 2,500 outbreaks annually,” Justman says.
The symptoms of stress-induced diarrhea are similar to what you’d experience from “regular” diarrhea—they’re just triggered by stress. Those include: Loose, watery stools
Treatment is supportive and based upon symptoms, with fluid and electrolyte replacement as the primary goal. Dehydration caused by diarrhea and vomiting is the most common complication. To prevent dehydration, it is important to take frequent sips of a rehydration drink (like water) or try to drink a cup of water or rehydration drink for each ...