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The bladder also contains β 3 adrenergic receptors, and pharmacological agonists of this receptor are used to treat overactive bladder. The mucosa of the urinary bladder may herniate through the detrusor muscle. [6] This is most often an acquired condition due to high pressure in the urinary bladder, damage, or existing connective tissue ...
Without diagnostic evaluation, the cause of underactive bladder is unclear, as there are multiple possible causes. UAB symptoms can accurately reflect impaired bladder emptying due either to DU or obstruction (normal or large storage volumes, elevated post-void residual volume), or can result from a sense of incomplete emptying of a hypersensitive bladder (small storage volumes, normal or ...
Bladder sphincter dyssynergia (also known as detrusor sphincter dyssynergia (DSD) (the ICS standard terminology agreed 1998) [1] and neurogenic detrusor overactivity (NDO)) is a consequence of a neurological pathology such as spinal injury [2] or multiple sclerosis [3] which disrupts central nervous system regulation of the micturition (urination) reflex resulting in dyscoordination of the ...
Neurogenic bladder can cause hydronephrosis (swelling of a kidney due to a build-up of urine), recurrent urinary tract infections, and recurrent kidney stones which may compromise kidney function. [7] This is especially significant in spastic neurogenic bladder that leads to high bladder pressures.
Atrophy of the detrusor muscle (atonic bladder is an extreme form) Hydronephrosis (congestion of the kidneys) Hypertrophy of the detrusor muscle (the muscle that squeezes the bladder to empty it during urination) Diverticula (formation of pouches) in the bladder wall (which can lead to stones and infection)
For example, a patient complaining of urinary urgency (or rushing to the toilet), with increased frequency of urination can have overactive bladder syndrome. The cause of this might be detrusor overactivity, in which the bladder muscle (the detrusor) contracts unexpectedly during bladder filling. Urodynamics can be used to confirm the presence ...
Bladder stone; Cancer of the bladder and prostate; Detrusor muscle weakness and/or instability; Diabetes; Use of ketamine [11] Neurological conditions; for example multiple sclerosis, spinal cord injury, cauda equina syndrome; Prostatitis, including IgG4-related prostatitis [12] [13] [14] Urethral stricture; Urinary tract infections (UTIs) [15]
The walls of the bladder have a series of ridges, thick mucosal folds known as rugae that allow for the expansion of the bladder. The detrusor muscle is the muscular layer of the wall made of smooth muscle fibers arranged in spiral, longitudinal, and circular bundles. [8] The detrusor muscle is able to change its length.