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  2. Bicarbonate - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate

    The bicarbonate ion (hydrogencarbonate ion) is an anion with the empirical formula HCO − 3 and a molecular mass of 61.01 daltons; it consists of one central carbon atom surrounded by three oxygen atoms in a trigonal planar arrangement, with a hydrogen atom attached to one of the oxygens. It is isoelectronic with nitric acid HNO 3.

  3. Ductal cells - Wikipedia

    en.wikipedia.org/wiki/Ductal_cells

    The primary function of pancreas ductal cells is to secrete a bicarbonate-rich, isotonic fluid. This fluid washes away the inactive form of digestive enzymes in the ductal system, neutralizes stomach acidity and mucins, and creates a pH environment necessary for the pancreas's normal function.

  4. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    Most of the carbonic acid then dissociates to bicarbonate and hydrogen ions. The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H 2 CO 3), bicarbonate ion (HCO − 3), and carbon dioxide (CO 2) in order to maintain pH in the blood and duodenum, among other tissues, to support proper ...

  5. Pancreatic juice - Wikipedia

    en.wikipedia.org/wiki/Pancreatic_juice

    The pancreas also receives autonomic innervation. The blood flow into pancreas is regulated by sympathetic nerve fibers, while parasympathetic neurons stimulate the activity of acinar and centroacinar cells. Pancreatic secretion is an aqueous solution of bicarbonate originating from the duct cells and enzymes originating from the acinar cells.

  6. Anion exchanger family - Wikipedia

    en.wikipedia.org/wiki/Anion_Exchanger_Family

    The anion exchanger family (TC# 2.A.31, also named bicarbonate transporter family) is a member of the large APC superfamily of secondary carriers. [1] Members of the AE family are generally responsible for the transport of anions across cellular barriers, although their functions may vary. All of them exchange bicarbonate. Characterized protein ...

  7. Centroacinar cell - Wikipedia

    en.wikipedia.org/wiki/Centroacinar_cell

    The exocrine pancreas is one of two compartments that include digestive-acting acinar cells and duct cells.They represent an extension of the intercalated duct into each pancreatic acinus. [1] These cells are commonly known as duct cells, and secrete an aqueous bicarbonate solution under stimulation by the hormone secretin. They also secrete ...

  8. Gastric acid - Wikipedia

    en.wikipedia.org/wiki/Gastric_acid

    The pancreas further produces large amounts of bicarbonate and secretes bicarbonate through the pancreatic duct to the duodenum to neutralize gastric acid passing into the digestive tract. The secretion is a complex and relatively energetically expensive process.

  9. Alkaline tide - Wikipedia

    en.wikipedia.org/wiki/Alkaline_tide

    The alkaline tide is neutralised by a secretion of H + into the blood during HCO 3 − secretion in the pancreas. [2] Postprandial (i.e., after a meal) alkaline tide lasts until the acids in food absorbed in the small intestine reunite with the bicarbonate that was produced when the food was in the stomach. Thus, alkaline tide is self-limited ...