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Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
Chemosis is the swelling (or edema) of the conjunctiva. The term derives from the Greek words cheme and -osis, cheme meaning cockleshell due to the swollen conjunctiva resembling it, and -osis meaning condition. [1] The swelling is due to the oozing of exudate from abnormally permeable capillaries. In general, chemosis is a nonspecific sign of ...
Oral administration of a liquid. In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration ...
Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor. [1] It is used to treat various eye diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and infections inside the eye such as endophthalmitis. [1]
Intravitreal administration is a route of administration of a drug, or other substance, in which the substance is delivered into the vitreous humor of the eye. "Intravitreal" literally means "inside an eye". Intravitreal injections were first introduced in 1911 when Ohm gave an injection of air into the vitreous humor to repair a detached retina.
An intracameral injection is usually of an antibiotic into the anterior chamber of the eyeball to prevent endophthalmitis caused by an infection of the eye that can occur after cataract surgery. The Food and Drug Administration (FDA) has not approved antibiotics for this use and it is considered 'off-label'.
Schematic diagram of the human eye showing. Subconjunctival injection is a type of periocular route of injection for ocular drug administration by administration of a medication either under the conjunctiva or underneath the conjunctiva lining the eyelid.
Drug instillation, also known as medication instillation, is the administration of a medicine, generally in liquid form either drop by drop or with a catheter into a body space or cavity. [1] Drop by drop administration may be done for eye drops , ear drops , or nose drops . [ 1 ]