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Orlistat (Xenical), the most commonly used medication to treat obesity and sibutramine (Meridia), a medication that was withdrawn due to cardiovascular side effects. Anti-obesity medication or weight loss medications are pharmacological agents that reduce or control excess body fat.
For instance, one Novo Nordisk-funded 2022 trial compared the weight loss effects of semaglutide with liraglutide. This trial looked at 338 non-diabetic adults who had obesity or overweight ...
Calories in vs. calories out play the largest role in weight loss (or gain). Beyond eating less, eating the right types of foods can also help with weight loss by making people feel more full.
Midodrine is a prodrug which forms the active metabolite, desglymidodrine, which is an α 1-adrenergic receptor agonist and exerts its actions via activation of α 1-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
Fenfluramine as a single drug was first introduced in the 1970s, but was not popular because it only temporarily reduced weight. [1] A 1984 study found a weight loss of 7.5 kg on average in 24 weeks, as compared to 4.4 kg under placebo. [4] It sold modestly until the 1990s, when it was combined with phentermine and heavily marketed. [1]
On the flip side, while there isn't scientific evidence of negative effects of this nature at this point, there is some anecdotal evidence linking GLP-1s and a decreased enthusiasm and drive when ...
Patients who receive the drug are also counseled on this potential side effect. Users of the popular weight loss drugs have already reported a number of side effects — from personality changes ...
Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, [1] [2] [3] and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a ...