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Hypoesthesia or numbness is a common side effect of various medical conditions that manifests as a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli. In everyday speech this is generally referred to as numbness.
Paresthesias are usually painless and can occur anywhere on the body, but most commonly occur in the arms and legs. [1] The most familiar kind of paresthesia is the sensation known as "pins and needles" after having a limb "fall asleep". A less well-known and uncommon paresthesia is formication, the sensation of insects crawling on the skin.
The following table describes the IENFD values in males and females of a 3 mm biopsy 10 cm above the lateral malleolus (above ankle outer side of leg). [21] Any value measured below the 0.05 Quantile IENFD values per age span, is considered a reliable positive diagnosis for small fiber peripheral neuropathy. [21]
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
These paresthesias may be painful, such as shooting pain, burning, or a dull ache. They may also be pain-free, such as numbness or tingling. Motor nerve entrapment may present with muscle weakness or paralysis for voluntary movements of the innervated muscles. Entrapment of certain pelvic nerves can cause incontinence and/or sexual dysfunction. [2]
Dysesthesia can include sensations in any bodily tissue, including most often the mouth, scalp, skin, or legs. [1] It is sometimes described as feeling like acid under the skin. Burning dysesthesia might accurately reflect an acidotic state in the synapses and perineural space.
Head trauma, Tumor, Stroke Focal neurologic signs , also known as focal neurological deficits or focal CNS signs , are impairments of nerve , spinal cord , or brain function that affects a specific region of the body, e.g. weakness in the left arm, the right leg, paresis , or plegia .
Signs and symptoms of peroneal nerve palsy are related to mostly lower legs and foot which are the following: [3] Decreased sensation, numbness, or tingling in the top of the foot or the outer part of the upper or lower leg; Foot drops (unable to hold the foot straight across) Toes drag while walking; Weakness of the ankles or feet; Prickling ...