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Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells , but also acts on haemopoietic progenitor cells and T cells .
54426 Ensembl ENSG00000109758 ENSMUSG00000029102 UniProt Q04756 Q9R098 RefSeq (mRNA) NM_001297439 NM_001528 NM_019447 RefSeq (protein) NP_001284368 NP_001519 NP_062320 Location (UCSC) Chr 4: 3.44 – 3.45 Mb Chr 5: 35.2 – 35.21 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Hepatocyte growth factor activator is a protein that in humans is encoded by the HGFAC gene. The protein ...
Human hepatocyte growth factor (HGF) is an 80kD [1] pleiotropic protein that is endogenously produced by a variety of cell types from the mesenchymal cell lineage (such as cardiomyocytes and neurons). [4] It is produced and proteolytically cleaved to its active state in response to cellular injury or during apoptosis.
A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation. [1] Usually it is a secreted protein or a steroid hormone .
9146 15239 Ensembl ENSG00000185359 ENSMUSG00000025793 UniProt O14964 Q99LI8 RefSeq (mRNA) NM_004712 NM_001159328 NM_008244 RefSeq (protein) NP_004703 NP_001152800 NP_032270 Location (UCSC) Chr 17: 81.68 – 81.7 Mb Chr 11: 120.36 – 120.37 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is ...
Jessica Capshaw and Camilla Luddington talk about their new podcast and reflect on their time on Grey's Anatomy. (Corbis via Getty Images) (Stephane Cardinale - Corbis via Getty Images)
Hepatocyte growth factor receptor (HGF receptor) [5] [6] is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. [7] The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor.
A car thief has been jailed for manslaughter after killing a 68-year-old man in east London with a single punch. Evaldas Simanaitis was found seriously injured outside his home in Leytonstone just ...
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