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Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life. Two segments of DNA can have shared ancestry because of three phenomena: either a speciation event (orthologs), or a duplication event (paralogs), or else a horizontal (or lateral) gene ...
The human genome is a complete set of nucleic acid sequences for humans, encoded as the DNA within each of the 24 distinct chromosomes in the cell nucleus. A small DNA molecule is found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. [1]
Alignments of multiple sequences are used to indicate which regions of each sequence are homologous. [40] Homologous sequences are orthologous if they are descended from the same ancestral sequence separated by a speciation event: when a species diverges into two separate species, the copies of a single gene in the two resulting species are ...
The pseudoautosomal regions or PARs are homologous sequences of nucleotides found within the sex chromosomes of species with an XY [1] or ZW [2] mechanism of sex determination. The pseudoautosomal regions get their name because any genes within them (so far at least 29 have been found for humans) [3] are inherited just like any autosomal genes.
Recombination hotspots are regions in a genome that exhibit elevated rates of recombination relative to a neutral expectation. The recombination rate within hotspots can be hundreds of times that of the surrounding region. [1] Recombination hotspots result from higher DNA break formation in these regions, and apply to both mitotic and meiotic ...
Homologous recombination is the proposed mechanism whereby the DNA virus human herpesvirus-6 integrates into human telomeres. [ 92 ] When two or more viruses, each containing lethal genomic damage, infect the same host cell, the virus genomes can often pair with each other and undergo homologous recombinational repair to produce viable progeny.
A 2007 study found that about 90% of the genes in the Abyssinian domestic cat are similar to humans. ... When it comes to insects' DNA, humans have a bit less in common. For example, fruit flies ...
Both the human region and the homologous chimpanzee region are encompassed by typical alpha-satellite DNA found near the chromosome centromeres. The first duplicative transposition occurred about 1.2mya with a second larger genomic sequence invert occurring 880,000ya.