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  2. Congenital insensitivity to pain - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    A patient and doctor discuss congenital insensitivity to pain. For people with this disorder, cognition and sensation are otherwise normal; for instance, patients can still feel discriminative touch (though not always temperature [3]), and there are generally no detectable physical abnormalities.

  3. Congenital insensitivity to pain with anhidrosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Since people with this condition are unable to sweat, they are unable to properly regulate their body temperature. [1] Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to lack of protective impulses ...

  4. Anhedonia - Wikipedia

    en.wikipedia.org/wiki/Anhedonia

    Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure. [1] While earlier definitions emphasized the inability to experience pleasure, anhedonia is currently used by researchers to refer to reduced motivation, reduced anticipatory pleasure (wanting), reduced consummatory pleasure (liking), and deficits in reinforcement learning.

  5. Marsili syndrome - Wikipedia

    en.wikipedia.org/wiki/Marsili_syndrome

    These individuals reported experiencing visceral pain, headaches and, when tested, didn't have an impaired ability to feel light touch, and (when also tested) had a reduced ability to feel capsaicin, which in turn let them eat spicy food calmly, which wouldn't be the case for people with normal pain sensation, and didn't suffer from congenital ...

  6. Hereditary sensory and autonomic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Hereditary_sensory_and...

    Many people with this condition have tingling, weakness, and a reduced ability to feel pain and sense hot and cold. Some affected individuals do not lose sensation, but instead feel shooting pains in their legs and feet. As the disorder progresses, the sensory abnormalities can affect the hands, arms, shoulders, and abdomen.

  7. Hereditary sensory and autonomic neuropathy type I - Wikipedia

    en.wikipedia.org/wiki/Hereditary_sensory_and...

    Since affected individuals cannot feel pain, minor wounds or blisters in the painless area may not be immediately recognized and can develop into extensive and deep foot ulcerations. Once infection occurs, the complications such as inflammation and progressive destruction of the underlying bones may follow and may require amputation of the ...

  8. Familial dysautonomia - Wikipedia

    en.wikipedia.org/wiki/Familial_dysautonomia

    Familial dysautonomia (FD), also known as Riley–Day syndrome, is a rare, [2] progressive, [3] recessive genetic disorder of the autonomic nervous system [2] that affects the development and survival of sensory, sympathetic, and some parasympathetic neurons in the autonomic and sensory nervous system.

  9. Pain disorder - Wikipedia

    en.wikipedia.org/wiki/Pain_disorder

    Pain disorder is chronic pain experienced by a patient in one or more areas, and is thought to be caused by psychological stress. The pain is often so severe that it disables the patient from proper functioning. Duration may be as short as a few days or as long as many years.