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Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
There's lots of confusion around the difference between vitamin D2 and vitamin D3, and which is best for whom. Doctors and experts explain. ... (that is, a very high dose given over a short period ...
“The other thing is that there were some questions about whether high doses might be beneficial of vitamin D and calcium,” Rao said. ... a day of supplemental vitamin D3 without calcium over ...
[9] [10] Vitamin-D supplements may not be effective in people with severe kidney disease. [11] [10] Excessive doses in humans can result in vomiting, constipation, muscle weakness, and confusion. [5] Other risks include kidney stones. [11] Doses greater than 40 000 IU (1000 μg) per day are generally required before high blood calcium occurs. [12]
Calcium and Vitamin D3 are often combined, with claims for adult bone health (This label predates current U.S. Food and Drug Administration regulations on health claims. [78]) Characteristics of osteomalacia are softening of the bones, leading to bending of the spine, bone fragility, and increased risk for fractures. [1]
The latest results compare bone fractures in those who took either a high dose — 2,000 international units of the most active form of vitamin D, called D-3 — or dummy pills every day for five ...
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