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  2. Cholic acid - Wikipedia

    en.wikipedia.org/wiki/Cholic_acid

    Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid [3] that is insoluble in water (soluble in alcohol and acetic acid), it is a white crystalline substance. Salts of cholic acid are called cholates.

  3. Bile acid sequestrant - Wikipedia

    en.wikipedia.org/wiki/Bile_acid_sequestrant

    Bile salt diarrhea can also be a side-effect of gallbladder removal. [1] Bile acid sequestrants are the principal therapy for bile acid-induced diarrhea. [7] [1] Cholestyramine, colestipol and colesevelam have all been used. Doses may not need to be as high as those previously used for hyperlipidemia.

  4. Gallstone - Wikipedia

    en.wikipedia.org/wiki/Gallstone

    A gallstone is a stone formed within the gallbladder from precipitated bile components. [2] The term cholelithiasis may refer to the presence of gallstones or to any disease caused by gallstones, [5] and choledocholithiasis refers to the presence of migrated gallstones within bile ducts. Most people with gallstones (about 80%) are asymptomatic.

  5. Ursodeoxycholic acid - Wikipedia

    en.wikipedia.org/wiki/Ursodeoxycholic_acid

    Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria.It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. [8]

  6. Bile acid - Wikipedia

    en.wikipedia.org/wiki/Bile_acid

    These conjugated bile acids are often referred to as bile salts. The pKa of the unconjugated bile acids are between 5 and 6.5, [ 4 ] and the pH of the duodenum ranges between 3 and 5, so when unconjugated bile acids are in the duodenum, they are almost always protonated (HA form), which makes them relatively insoluble in water.

  7. Chenodeoxycholic acid - Wikipedia

    en.wikipedia.org/wiki/Chenodeoxycholic_acid

    Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the main bile acids. Chenodeoxycholic acid is one of the main bile acids. [ 1 ] [ 2 ] [ 3 ] It was first isolated from the bile of the domestic goose, which gives it the "cheno" portion of its name (Greek: χήν = goose).

  8. Colesevelam - Wikipedia

    en.wikipedia.org/wiki/Colesevelam

    Colesevelam is part of a class of drugs known as bile acid sequestrants. Colesevelam hydrochloride, the active pharmaceutical ingredient in Welchol, is a non-absorbed, lipid-lowering polymer that binds bile acids in the intestine, impeding their reabsorption. As the bile acid pool becomes depleted, the hepatic enzyme, cholesterol 7-α ...

  9. Calculus (medicine) - Wikipedia

    en.wikipedia.org/wiki/Calculus_(medicine)

    Calculi of the gallbladder and bile ducts are called gallstones and are primarily developed from bile salts and cholesterol derivatives. Calculi in the nasal passages are rare. Calculi in the gastrointestinal tract (enteroliths) can be enormous. Individual enteroliths weighing many pounds have been reported in horses.

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