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The ingestion of neem oil is potentially toxic and can cause metabolic acidosis, seizures, kidney failure, encephalopathy and severe brain ischemia in infants and young children. [2] [8] [9] Neem oil should not be consumed alone without any other solutions, particularly by pregnant women, women trying to conceive or children. [2]
This molecule can also be found in neem oil at 0.12%. [3] Among the metabolites present in neem, nimbin is the least present chemical compound. [15] Nimbin biosynthesis is not influenced by environmental conditions [17] (temperature, rainfall, humidity…) because neem trees from the same agro-climatic zone can have very different nimbin ...
Kidney toxicity [5] associated with kidney failure; associated with development of cancer, particularly of the urinary tract, known carcinogen [8] [9] Atractylate Atractylis gummifera: Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10]
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Though recipes can vary, "many of the sweets on this list also use vegetable oils (e.g. soybean oil, canola oil), which tend to have excessive amounts of omega-6."
Azadirachtin, a chemical compound belonging to the limonoid group, is a secondary metabolite present in neem seeds. It is a highly oxidized tetranortriterpenoid which boasts a plethora of oxygen-bearing functional groups, including an enol ether , acetal, hemiacetal , tetra-substituted epoxide and a variety of carboxylic esters .
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