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The signs and symptoms of TTP may at first be subtle and nonspecific. Many people experience an influenza-like or diarrheal illness before developing TTP. [7] Neurological symptoms are very common and vary greatly in severity. Frequently reported symptoms include feeling very tired, confusion, and headaches. [7]
3 Treatment. 4 See also. 5 ... Another form is thrombotic thrombocytopenic purpura. ... Diagnosis is done by the help of symptoms and only blood count abnormality is ...
ITP is usually chronic in adults [60] and the probability of durable remission is 20–40 percent. [19] The male to female ratio in the adult group varies from 1:1.2 to 1.7 in most age ranges (childhood cases are roughly equal for both sexes) and the median age of adults at the diagnosis is 56–60. [12]
The classic TMAs are hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Other conditions with TMA include atypical hemolytic uremic syndrome, disseminated intravascular coagulation, scleroderma renal crisis, malignant hypertension, antiphospholipid antibody syndrome, and drug toxicities, e.g. calcineurin inhibitor toxicity. [1]
Treatment of thrombotic thrombocytopenic purpura (TTP) is a medical emergency, since the associated hemolytic anemia and platelet activation can lead to kidney failure and changes in the level of consciousness. Treatment of TTP was revolutionized in the 1980s with the application of plasmapheresis.
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Without treatment, necrotic soft tissue may become gangrenous, leading to loss of limbs. [2] Purpura fulminans is often accompanied by micro-vascular thrombosis and haemorrhagic infarction in other tissues, such as the lungs , kidneys , central nervous system and adrenal glands , leading to multiple organ failure, and causes initial high ...
“The brain may get OK with time in some persons. But it’s hard to find a person who has completely normal brain function after a long cycle of opiate addiction, not without specific medication treatment.” An abstinence-only treatment that may have a higher success rate for alcoholics simply fails opiate addicts.
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