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An intracameral injection is usually of an antibiotic into the anterior chamber of the eyeball to prevent endophthalmitis caused by an infection of the eye that can occur after cataract surgery. The Food and Drug Administration (FDA) has not approved antibiotics for this use and it is considered 'off-label'.
Antibiotic ointment is typically applied to the newborn's eyes within 1 hour of birth as prevention for gonococcal ophthalmia. [3] This practice is recommended for all newborns and most hospitals in the United States are required by state law to apply eye drops or ointment soon after birth to prevent the disease.
Where insufficient intravenous antibiotics are given before delivery, the baby may be given antibiotics immediately after birth, although evidence is inconclusive as to whether this practice is effective or not. [12] [59] [60] [61] Falling incidence of EOD and LOD GBS disease in US-CDC
Neonatal infections may be contracted by mother to child transmission, in the birth canal during childbirth, or after birth. [2] Neonatal infections may present soon after delivery, or take several weeks to show symptoms. Some neonatal infections such as HIV, hepatitis B, and malaria do not become apparent until much later.
Antibiotics have been used to prevent and treat these infections—however, the misuse of antibiotics is a serious problem for global health. [2] It is recommended that guidelines be followed that outline when it is appropriate to give antibiotics and which antibiotics are most effective. [2]
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