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Armodafinil, sold under the brand name Nuvigil, is a wakefulness-promoting medication which is used to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. [1] It is also used off-label for certain other indications. [10] The drug is taken by mouth. [1]
Evidence for a positive effect of CBT has been found in trials for fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome, unexplained headaches, unexplained back pain, tinnitus, and non-cardiac chest pain. [25] Overall, CBT has been shown to be effective in reducing psychological distress and improving medical status in MUPS patients.
Tinnitus is described as hearing a sound when an external sound is not present. [13] Noise-induced hearing loss can cause high-pitched tinnitus. [14] An estimated 50 million Americans have some degree of tinnitus in one or both ears; 16 million of them have symptoms serious enough for them to see a doctor or hearing specialist.
Muscle tension, particularly in the jaw muscles like the masseter and medial pterygoid, can radiate to the ears, leading to somatic tinnitus. Specialized physical therapists use neuromuscular techniques to alleviate tension in these areas, which may reduce tinnitus intensity and associated pain in connected areas, such as the jaw, teeth, and ears.
[5] [6] [7] This mechanism of action is unique among antiepileptic drugs, and may hold promise for the treatment of other neurologic conditions, including tinnitus, migraine and neuropathic pain. The manufacturer withdrew retigabine from clinical use in 2017.
As this enzyme is inhibited, prostaglandin and thromboxane production is reduced, hence inhibiting the inflammatory response of pain and swelling caused by prostaglandin. [19] Studies have proven that high-dose usage of aspirin can be associated with ototoxicity, manifesting reversible hearing loss and tinnitus. [20]
Armodafinil (Nuvigil, CRL-40982, CEP-10952, (R)-modafinil) – the (R)-enantiomer of modafinil Modafinil (Provigil, Alertec, Modavigil, CRL-40476) – a racemic mixture of armodafinil and esmodafinil Discontinued
Tinnitus Retraining Therapy or TRT, Round and Oval Window Reinforcement Hyperacusis is an increased sensitivity to sound and a low tolerance for environmental noise. Definitions of hyperacusis can vary significantly; it often revolves around damage to or dysfunction of the stapes bone , stapedius muscle or tensor tympani ( eardrum ).
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