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Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity. [1] This can cause heart failure, arrhythmia, myocarditis, and cardiomyopathy in patients. [2] Some effects are reversible, while in others, permanent damage requiring further treatment may arise.
Together, these events can lead to congestive heart failure and decrease the heart's output of blood with each squeeze. [10] Takotsubo cardiomyopathy occurs worldwide. [11] The condition is thought to be responsible for 2% of all acute coronary syndrome cases presenting to hospitals. [11]
Cardiomyopathies are either confined to the heart or are part of a generalized systemic disorder, both often leading to cardiovascular death or progressive heart failure-related disability. Other diseases that cause heart muscle dysfunction are excluded, such as coronary artery disease, hypertension, or abnormalities of the heart valves. [17]
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]
Heart failure is a chronic condition affecting about 6.2 million Americans. It occurs when the heart muscle is damaged—sometimes from something you can’t control, like an injury, virus, or ...
Eventually, heart failure can result, which carries a 50% mortality rate. [21] There is no effective treatment against established cardiomyopathy caused by the drug as of 2010. [21] The drug dexrazoxane, which is an iron chelator may be used to decrease the risk of doxorubicin's cardiotoxicity in certain cases. [22]
Heart failure has historically been irreversible, but a new study suggests that could change. At the University of Utah, scientists used a new gene therapy that reversed heart failure in animals.
3. Medications. Some medications have been associated with temporary hair loss. Most of the time hair loss related to medication is due to the drug disrupting the hair growth cycle leading to a ...
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