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  2. Mendelian traits in humans - Wikipedia

    en.wikipedia.org/wiki/Mendelian_traits_in_humans

    Therefore no trait is purely Mendelian, but many traits are almost entirely Mendelian, including canonical examples, such as those listed below. Purely Mendelian traits are a minority of all traits, since most phenotypic traits exhibit incomplete dominance, codominance, and contributions from many genes.

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    An individual with the sickle cell trait shows incomplete dominance when the shape of the red blood cell is considered. This is because the sickling happens only at low oxygen concentrations. With regards to the actual concentration of hemoglobin in the circulating cells, the alleles demonstrate co-dominance as both 'normal' and mutant forms co ...

  4. Non-Mendelian inheritance - Wikipedia

    en.wikipedia.org/wiki/Non-Mendelian_inheritance

    Individuals can develop a recessive trait in the phenotype dependent on their sex—for example, colour blindness and haemophilia (see gonosomal inheritances). [ 7 ] [ 8 ] As many of the alleles are dominant or recessive, a true understanding of the principles of Mendelian inheritance is an important requirement to also understand the more ...

  5. Simple Mendelian genetics in humans - Wikipedia

    en.wikipedia.org/wiki/Simple_Mendelian_genetics...

    Mendelian traits behave according to the model of monogenic or simple gene inheritance in which one gene corresponds to one trait. Discrete traits (as opposed to continuously varying traits such as height) with simple Mendelian inheritance patterns are relatively rare in nature, and many of the clearest examples in humans cause disorders .

  6. Mendelian inheritance - Wikipedia

    en.wikipedia.org/wiki/Mendelian_inheritance

    Indeed, many organisms have traits whose inheritance works differently from the principles he described; these traits are called non-Mendelian. [44] [45] For example, Mendel focused on traits whose genes have only two alleles, such as "A" and "a". However, many genes have more than two alleles. He also focused on traits determined by a single gene.

  7. Dominance (genetics) - Wikipedia

    en.wikipedia.org/wiki/Dominance_(genetics)

    Autosomal dominant and autosomal recessive inheritance, the two most common Mendelian inheritance patterns. An autosome is any chromosome other than a sex chromosome.. In genetics, dominance is the phenomenon of one variant of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome.

  8. Punnett square - Wikipedia

    en.wikipedia.org/wiki/Punnett_square

    These tables can be used to examine the genotypical outcome probabilities of the offspring of a single trait (allele), or when crossing multiple traits from the parents. The Punnett square is a visual representation of Mendelian inheritance, a fundamental concept in genetics discovered by Gregor Mendel. [10]

  9. Pleiotropy - Wikipedia

    en.wikipedia.org/wiki/Pleiotropy

    Pleiotropy seems limited for many traits in humans since the SNP overlap, as measured by variance accounted for, between many polygenic predictors is small. Most genetic traits are polygenic in nature: controlled by many genetic variants, each of small effect. These genetic variants can reside in protein coding or non-coding regions of the genome.