Search results
Results from the WOW.Com Content Network
Fetal hydantoin syndrome, also called fetal dilantin syndrome, is a group of defects caused to the developing fetus by exposure to teratogenic effects of phenytoin. Dilantin is the brand name of the drug phenytoin sodium in the United States, commonly used in the treatment of epilepsy.
The mechanism of action of phenytoin sodium. Sodium channels are: 1) Closed 2) Open 3) Inactive (phenytoin effect) Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels. [46] This blocks sustained high frequency repetitive firing of action potentials. This is accomplished by ...
Myotonia congenita is a congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder.The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles and rigidity. [1]
During pregnancy, the metabolism of many anticonvulsants is affected. There may be an increase in the clearance and resultant decrease in the blood concentration of lamotrigine, phenytoin, and to a lesser extent carbamazepine, and possibly decreases the level of levetiracetam and the active oxcarbazepine metabolite, the monohydroxy derivative. [94]
The risk of first-degree relatives developing the same hypersensitivity reaction is higher than in the general population. [ 1 ] As this syndrome can present secondary to multiple anticonvulsants, the general term "anticonvulsant hypersensitivity syndrome" (AHS) is favored over the original descriptive term "dilantin hypersensitivity syndrome."
Texas has sued a New York doctor for allegedly prescribing abortion pills to a Dallas-area woman, launching the first known legal challenge of its kind, which will test what happens when two ...
A U.S. appeals court has rejected British socialite Ghislaine Maxwell's request to revisit its decision upholding her conviction for helping the late financier Jeffrey Epstein sexually abuse ...
There are a few foods you may want to skip on Thanksgiving if you're taking a GLP-1 medication such as Ozempic, dietician Kylie Bensley, founder of the women’s nutrition company, Sulinu, tells ...