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Tissue-type plasminogen activator, short name tPA, is a protein that facilitates the breakdown of blood clots. It acts as an enzyme to convert plasminogen into its active form plasmin, the major enzyme responsible for clot breakdown. It is a serine protease (EC 3.4.21.68) found on endothelial cells lining the blood vessels.
Plasminogen activator inhibitor-1 is a serine protease, synthesized by endothelial cells, that specifically inhibits tissue plasminogen activator (tPA) and urokinase (uPA). Tissue plasminogen activator and urokinase are the activators of plasminogen and result in the breakdown of blood clots ( fibrinolysis ).
Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein was discovered, but not named, by McFarlane and Pilling in 1947. [ 5 ]
When you buy a bottle of vitamins from a nutrition store, you’ll probably notice a best-by date on the bottom of the jar. But that inscribed number isn’t a hard-and-fast rule—there is some ...
Herbalife Nutrition products. Herbalife Nutrition's products include weight-loss and protein shakes, [37] as well as protein bars, teas, aloes, vitamins, and sports hydration, energy, and personal care products. [38] The company's original product is the Formula 1 protein shake, a soy-based meal-replacement shake. The product debuted in 1980 ...
(Reuters) - The U.S. Food and Drug Administration on Wednesday approved Mesoblast's cell therapy for treating a type of complication that occurs after a stem cell or bone marrow transplant called ...
A study published last year found that a healthy diet could increase lifespan by up to 10 years, and Nathan K. LeBrasseur, a physiologist at Mayo Clinic, previously told BI that spending just 3% ...
Catabolite activator protein (CAP; also known as cAMP receptor protein, CRP) is a trans-acting transcriptional activator that exists as a homodimer in solution. Each subunit of CAP is composed of a ligand -binding domain at the N-terminus (CAP N , residues 1–138) and a DNA-binding domain at the C-terminus (DBD, residues 139–209).