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Intravenous sugar solution, also known as dextrose solution, is a mixture of dextrose (glucose) and water. [1] It is used to treat low blood sugar or water loss without electrolyte loss. [ 2 ] Water loss without electrolyte loss may occur in fever , hyperthyroidism , high blood calcium , or diabetes insipidus . [ 2 ]
Therefore, significant hypernatremia should be treated carefully by a physician or other medical professional with experience in treatment of electrolyte imbalance. Specific treatments such as thiazide diuretics (e.g., chlorthalidone) in congestive heart failure or corticosteroids in nephropathy also can be used. [19]
Patients with extra-renal salt losses complicated by hyponatremia were found to be common-place, and consistent with McCance's description, they excreted urine virtually free of sodium. [22] In 1950, Sims et al, published their work that suggest observed relation between hyponatremia and pulmonary tuberculosis.
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Intravenous sugar solutions, such as those containing glucose (also called dextrose), have the advantage of providing some energy, and may thereby provide the entire or part of the energy component of parenteral nutrition. Types of glucose/dextrose include: D5W (5% dextrose in water), which consists of 278 mmol/L dextrose
A 2004 statement by the European Society for Paediatric Endocrinology and the Lawson Wilkins Pediatric Endocrine Society (for children) uses slightly different cutoffs, where mild DKA is defined by pH 7.20–7.30 (bicarbonate 10–15 mmol/L), moderate DKA by pH 7.1–7.2 (bicarbonate 5–10) and severe DKA by pH<7.1 (bicarbonate below 5).
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This can reduce glucose availability and lead to hypoglycemia and increased reliance on fatty acid and ketone metabolism. [ 1 ] [ 5 ] An additional stressor such as vomiting or dehydration can cause an increase in counterregulatory hormones such as glucagon , cortisol and growth hormone which may further increase free fatty acid release and ...