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  2. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. [ 1 ] [ 2 ] Other terms include transaminasemia , [ 3 ] and elevated liver enzymes (though they are not the only enzymes in the liver).

  3. AST/ALT ratio - Wikipedia

    en.wikipedia.org/wiki/AST/ALT_ratio

    An AST/ALT ratio >5 necessarily involves extrahepatic tissue, as death of hepatocytes alone would produce an AST/ALT ratio no greater than 2.5. [9] Because the primary cause is extrahepatic, typically an isolated elevated AST is seen, with no change in ALT. Common causes include bone disease, chronic renal failure, lymphoma, and congestive ...

  4. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    This wide range of AST containing organs makes it a relatively less specific indicator of liver damage compared to ALT. An increase of mitochondrial AST in bloods is highly suggestive of tissue necrosis in myocardial infarction and chronic liver disease. More than 80% of the liver AST activity are contributed by mitochondrial form of the ...

  5. Alanine transaminase - Wikipedia

    en.wikipedia.org/wiki/Alanine_transaminase

    Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [1]

  6. Aspartate transaminase - Wikipedia

    en.wikipedia.org/wiki/Aspartate_transaminase

    Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954.

  7. Hepatitis - Wikipedia

    en.wikipedia.org/wiki/Hepatitis

    [70] [71] Generally, AST and ALT are elevated in most cases of hepatitis regardless of whether the person shows any symptoms. [32] The degree of elevation (i.e. levels in the hundreds vs. in the thousands), the predominance for AST vs. ALT elevation, and the ratio between AST and ALT are informative of the diagnosis. [32]

  8. 5 Items From the 1970s That Are Worth a Lot of Money - AOL

    www.aol.com/5-items-1970s-worth-lot-170007423.html

    Collectors and enthusiasts alike are willing to pay high prices or even top dollar for well-preserved, authentic pieces. Here are five valuable 1970s collectibles you might just have stored in ...

  9. Transaminase - Wikipedia

    en.wikipedia.org/wiki/Transaminase

    [citation needed] For example, the presence of elevated transaminases can be an indicator of liver and cardiac damage. Two important transaminase enzymes are aspartate transaminase (AST), also known as serum glutamic oxaloacetic transaminase (SGOT); and alanine transaminase (ALT), also called alanine aminotransferase (ALAT) or serum glutamate ...

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