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  2. Double minute - Wikipedia

    en.wikipedia.org/wiki/Double_minute

    An extensive cancer database search found that about 1.4% of all cases are positive for DMs, and out of cancer types, neuroblastoma has the highest frequency of DMs at 31.7%. [10] The amplification of specific genes that support the growth of tumor cells, such as oncogenes or drug-resistant genes, is critical to the cell adoption of malignancy ...

  3. Extrachromosomal DNA - Wikipedia

    en.wikipedia.org/wiki/Extrachromosomal_DNA

    Multiple forms of extrachromosomal DNA exist, and, while some of these serve important biological functions, [1] they can also play a role in diseases such as cancer. [2] [3] [4] In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids, whereas, in eukaryotes extrachromosomal DNA is primarily found in organelles. [1]

  4. Oncogenomics - Wikipedia

    en.wikipedia.org/wiki/Oncogenomics

    Oncogenomics is a sub-field of genomics that characterizes cancer-associated genes.It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.

  5. Paul Mischel - Wikipedia

    en.wikipedia.org/wiki/Paul_Mischel

    Paul S. Mischel (born July 13, 1962) is a physician-scientist whose laboratory has made pioneering discoveries in the pathogenesis of human cancer. [1] He is the Fortinet Founders Professor, and Vice Chair for Research for the Department of Pathology, Stanford Medicine, an Institute Scholar in Sarafan ChEM-H.

  6. Gene amplification - Wikipedia

    en.wikipedia.org/wiki/Gene_amplification

    In research or diagnosis DNA amplification can be conducted through methods such as: Polymerase chain reaction , an easy, cheap, and reliable way to repeatedly replicate a focused segment of DNA by polymerizing nucleotides, a concept which is applicable to numerous fields in modern biology and related sciences.

  7. The Cancer Genome Atlas - Wikipedia

    en.wikipedia.org/wiki/The_Cancer_Genome_Atlas

    The Cancer Genome Atlas (TCGA) is a project to catalogue the genomic alterations responsible for cancer using genome sequencing and bioinformatics. [1] [2] The overarching goal was to apply high-throughput genome analysis techniques to improve the ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of the disease.

  8. This Body Type Is Linked to an Increased Risk of Developing ...

    www.aol.com/lifestyle/body-type-linked-increased...

    Related: Shark Tank's Barbara Corcoran Recalls Caregiving for Her Mom with Alzheimer’s: 'Grieving in Slow Motion' (Exclusive) Alzheimer’s is the most common type of dementia, the U.S. Centers ...

  9. Myxofibrosarcoma - Wikipedia

    en.wikipedia.org/wiki/Myxofibrosarcoma

    Most cases of MFS have tumor cells that contain complex chromosome and/or gene abnormalities [7] including ring chromosomes (i.e. chromosome whose ends are fused together to form a ring), double minutes (i.e. small fragments of extrachromosomal DNA), chromosomes with deletions of part of their genetic material, and chromosome translocations (i ...