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Superior vena cava syndrome (SVCS), is a group of symptoms caused by obstruction of the superior vena cava ("SVC"), a short, wide vessel carrying circulating blood into the heart. The majority of cases are caused by malignant tumors within the mediastinum , most commonly lung cancer and non-Hodgkin's lymphoma , directly compressing or invading ...
A positive Pemberton's sign is indicative of superior vena cava syndrome (SVC), commonly the result of a mass in the mediastinum.Although the sign is most commonly described in patients with substernal goiters where the goiter "corks off" the thoracic inlet, [4] the maneuver is potentially useful in any patient with adenopathy, tumor, or fibrosis involving the mediastinum.
The subclavian vein is a big vessel that drains the blood from the hand, forearm and the upper arm into the right side of the heart through superior vena cava. The subclavian veins lie just behind the clavicle on each side and therefore known as subclavian vein.
The superior vena cava (SVC) is the superior of the two venae cavae, the great venous trunks that return deoxygenated blood from the systemic circulation to the right atrium of the heart. It is a large-diameter (24 mm) short length vein that receives venous return from the upper half of the body, above the diaphragm .
If obstruction of the superior vena cava by the Pancoast tumor occurs, a resulting mass effect called the superior vena cava syndrome occurs, resulting in facial swelling cyanosis and dilatation of the veins of the head and neck. This syndrome can be seen in 5-10% of patient cases. [11]
Facial plethora may be a sign of Cushing's syndrome, superior vena cava syndrome, carcinoid syndrome, polycythemia vera, and rosacea. In superior vena cava syndrome compression of the vein causes upper body swelling that can lead to facial plethora.
Tonofibrils seen under electron microscopy can differentiate thymoma from other tumors such as carcinoid, Hodgkin's, and seminoma. Patients are usually asymptomatic but can present with myasthenia gravis-related symptoms, substernal pain, dyspnea, or cough. Invasive tumors can produce compression effects such as superior vena cava syndrome.
right - superior vena cava, right brachiocephalic vein, and pleura; left - left common carotid artery and thymus; The thymus typically sits atop the brachiocephalic artery, and it separates the artery from the posterior surface of the manubrium of sternum. [4]
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