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Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
Cyproheptadine, a non-selective serotonin receptor antagonist (including of the serotonin 5-HT 2A receptor), is used as an antidote in the treatment of serotonin syndrome (or serotonin toxicity) caused by serotonergic drugs, including the toxicity of serotonergic psychedelics like the NBOMe drugs.
Here are links to possibly useful sources of information about Cyproheptadine. PubMed provides review articles from the past five years (limit to free review articles ) The TRIP database provides clinical publications about evidence-based medicine .
Cyproheptadine blocks 5-HT 2A, H1 and is a mild anticholinergic. Methysergide is a 5-HT 2A antagonist and nonselective 5-HT 1 receptor blocker. It causes retroperitoneal fibrosis and mediastinal fibrosis. [citation needed] Quetiapine blocks 5-HT 2A, 5-HT 1A, dopamine receptors D 1 and D 2, histamine receptor H1, and A1 adrenoreceptors.
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Oklahoma death row inmate, Kevin Ray Underwood, 44, is set to be executed Thursday, 18 years after he killed 10-year-old neighbor Jamie Rose Bolin.
The following other wikis use this file: Usage on ar.wikipedia.org سيبروهيبتادين; Usage on azb.wikipedia.org سیپروهپتادین
Shirts, mugs and stickers bearing the words "Deny Defend Depose" are appearing for sale on e-commerce websites just days after UnitedHealthcare CEO Brian Thompson was shot to death in New York City.