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Tetrahydrocannabinol (THC) is the primary psychoactive component of the Cannabis plant. Delta-9-tetrahydrocannabinol (Δ 9-THC, THC) and delta-8-tetrahydrocannabinol (Δ 8-THC), through intracellular CB 1 activation, induce anandamide and 2-arachidonoylglycerol synthesis produced naturally in the body and brain [citation needed] [dubious ...
[26] Her story has led to her being described as "the girl who is changing medical marijuana laws across America," [6] as well as the "most famous example of medicinal hemp use". [52] On November 13, 2019, Charlotte was the first child featured on the cover of High Times magazine in her "Namesake" role as a "High Times Female 50" award nominee.
Hash oil or cannabis oil is an oleoresin obtained by the extraction of cannabis or hashish. [1] It is a cannabis concentrate containing many of its resins and terpenes – in particular, tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids .
Nabiximols (brand name Sativex), an oromucosal spray made of a complex botanical mixture containing cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), and additional cannabinoid and non-cannabinoid constituents from cannabis sativa plants, was approved by Health Canada in 2005, to treat central neuropathic pain in multiple sclerosis, and in ...
A cannabis edible, also known as a cannabis-infused food or simply an edible, is a food item (either homemade or produced commercially) that contains decarboxylated cannabinoids (cannabinoid acids converted to their orally bioactive form) from cannabis extract as an active ingredient. [1]
Δ 9-tetrahydrocannabinol (THC) Cannabis sativa, scientific drawing from c. 1900 Although the main psychoactive constituent of Cannabis is tetrahydrocannabinol (THC), the plant is known to contain more than 500 compounds, among them at least 113 cannabinoids ; however, most of these "minor" cannabinoids are only produced in trace amounts. [ 9 ]
These are achieved at lower doses, because many synthetic cannabinoids are more potent than marijuana, and users are often unaware of exactly what they are getting and how potent it is. [55] For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8]
2022: Legislation is passed to allow the sale and consumption of food and beverage products containing 5 mg of THC per serving and 50 mg per package. [ 105 ] 2023: Governor Tim Walz signs House File 100 to legalize cannabis for recreational use, effective August 1, 2023.