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Rh(D) status of an individual is normally described with a positive (+) or negative (−) suffix after the ABO type (e.g., someone who is A+ has the A antigen and Rh(D) antigen, whereas someone who is A− has the A antigen but lacks the Rh(D) antigen). The terms Rh factor, Rh positive, and Rh negative refer to the Rh(D
Involvement of the spinal joints is more suggestive of psoriatic arthritis than rheumatoid arthritis. [3] Rheumatoid factor (RF) and cyclic citrullinated peptide autoantibodies are typically found in the blood of people with RA, but not, as a rule, in those with PsA. [16] [17] Comorbities may help differential diagnosis. [17]
Factor XII (Hageman Factor) Liver: A protein that circulates inactively, until activated by collagen, platelets, or exposed basement membranes via conformational change. When activated, it in turn is able to activate three plasma systems involved in inflammation: the kinin system, fibrinolysis system, and coagulation system. Membrane attack complex
For instance, in rheumatoid arthritis, an autoimmune disease primarily affecting the joints, symptoms typically include joint pain, swelling, and stiffness. On the other hand, type 1 diabetes, which results from an autoimmune attack on the insulin-producing cells of the pancreas, primarily presents with symptoms related to high blood sugar ...
10921 19826 Ensembl ENSG00000205937 ENSMUSG00000034681 UniProt Q15287 Q99M28 RefSeq (mRNA) NM_001286625 NM_001286626 NM_001286627 NM_006711 NM_080594 NM_001080127 NM_001080128 NM_009070 NM_001357626 RefSeq (protein) NP_001273554 NP_001273555 NP_001273556 NP_006702 NP_542161 NP_001073596 NP_001073597 NP_033096 NP_001344555 Location (UCSC) Chr 16: 2.25 – 2.27 Mb Chr 17: 24.63 – 24.64 Mb ...
1401 12944 Ensembl ENSG00000132693 ENSMUSG00000037942 UniProt P02741 P14847 RefSeq (mRNA) NM_000567 NM_001329057 NM_001329058 NM_001382703 NM_007768 RefSeq (protein) NP_000558 NP_001315986 NP_001315987 NP_001369632 NP_031794 Location (UCSC) Chr 1: 159.71 – 159.71 Mb Chr 1: 172.53 – 172.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse C-reactive protein (CRP) is an annular (ring ...
Obesity itself is a medical condition and not a disease, but it constitutes a major risk factor for developing chronic illnesses, such as diabetes, stroke, cardiovascular disease and cancers. Obesity results in significant health care spending and indirect costs, as illustrated by a recent study from the Texas comptroller reporting that obesity ...
Radiation exposure such as ultraviolet radiation and radioactive material is a risk factor for cancer. [69] [70] [71] Many non-melanoma skin cancers are due to ultraviolet radiation, mostly from sunlight. [70] Sources of ionizing radiation include medical imaging and radon gas. [70] Ionizing radiation is not a particularly strong mutagen. [72]