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Mallet-Guy's sign is a medical sign to detect signs of pancreatitis. [1] It is pain elicited with deep palpation of the left subcostal and epigastric region, suggesting pancreatic inflammation. It is named after Pierre Mallet-Guy .
The test for amylase is easier to perform than that for lipase, making it the primary test used to detect and monitor pancreatitis. Medical laboratories will usually measure either pancreatic amylase or total amylase. If only pancreatic amylase is measured, an increase will not be noted with mumps or other salivary gland trauma.
A lipid profile or lipid panel is a panel of blood tests used to find abnormalities in blood lipid ( such as cholesterol and triglycerides) concentrations. [not verified in body] The results of this test can identify certain genetic diseases and can determine approximate risks for cardiovascular disease, certain forms of pancreatitis, and other diseases.
In chronic pancreatitis, these tests may be normal. [1] Medical imaging such as ultrasound and CT scan may also be useful. [1] Acute pancreatitis is usually treated with intravenous fluids, pain medication, and sometimes antibiotics. [1] Typically eating and drinking are disallowed, and a nasogastric tube is placed in the stomach. [1]
Blood tests for lipase may be used to help investigate and diagnose acute pancreatitis and other disorders of the pancreas. [32] Measured serum lipase values may vary depending on the method of analysis. [citation needed] Lipase assist in the breakdown of fats in those undergoing pancreatic enzyme replacement therapy (PERT).
Acute pancreatitis (AP) is a sudden inflammation of the pancreas.Causes include a gallstone impacted in the common bile duct or the pancreatic duct, heavy alcohol use, systemic disease, trauma, elevated calcium levels, hypertriglyceridemia (with triglycerides usually being very elevated, over 1000 mg/dL), certain medications, hereditary causes and, in children, mumps.
In pancreatitis, enzymes of the exocrine pancreas damage the structure and tissue of the pancreas. Detection of some of these enzymes, such as amylase and lipase in the blood, along with symptoms and findings on medical imaging such as ultrasound or a CT scan, are often used to indicate that a
Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions. [1] It can present as episodes of acute inflammation in a previously injured pancreas , or as chronic damage with persistent pain or malabsorption .