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The three results are usually reported together. A low transferrin saturation is a common indicator of iron deficiency anemia whereas a high transferrin saturation may indicate iron overload or hemochromatosis. [1] [2] Transferrin saturation is also called transferrin saturation index (TSI) or transferrin saturation percentage (TS%) [3]
Low, as there is excess transferrin with normal serum iron levels. These examples demonstrate that to properly understand a value for TIBC, one also must know the serum iron, the percent transferrin saturation, and the individual clinical situation.
When plasma transferrin levels rise, there is a reciprocal decrease in percent transferrin iron saturation, and a corresponding increase in total iron binding capacity in iron deficient states [22] A decreased plasma transferrin level can occur in iron overload diseases and protein malnutrition.
In spite of an increased level of transferrin, serum iron level is decreased along with transferrin saturation. Erythropoiesis impairment begins when the serum iron level falls to less than 50 μg/dL and transferrin saturation is less than 16%. [4] In stage 3, anemia (reduced hemoglobin levels) is present but red blood cell appearance remains ...
The percentage of iron saturation (or transferrin saturation index or percent) can be measured by dividing the level of serum iron by total iron binding capacity and is a value that can help to confirm the diagnosis of iron-deficiency anemia; however, other conditions must also be considered, including other types of anemia. [18]
One’s biological age, which measures the body’s physiological state, may help predict who is at risk for developing colon polyps, a known risk factor for colorectal cancer.
Transferrin and TIBC Transferrin saturation Ferritin Transferrin receptor Related tests Hb MCV Iron deficiency anemia: Iron overload (hemochromatosis) * Normal Anemia of chronic disease * * Porphyria cutanea tarda (PCT) Normal Thalassemia Sideroblastic anemia * Megaloblastic anemia: Hemolytic anemia * * * * Pregnancy or use of
3. Plan your withdrawal strategy. Most retirement strategies plan for saving, not spending. So it’s not always easy to remember that there will come a time you have to spend the money you’ve ...
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