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  2. Mutagen - Wikipedia

    en.wikipedia.org/wiki/Mutagen

    Other carcinogens may cause cancer through a variety of mechanisms without producing mutations, such as tumour promotion, immunosuppression that reduces the ability to fight cancer cells or pathogens that can cause cancer, disruption of the endocrine system (e.g. in breast cancer), tissue-specific toxicity, and inflammation (e.g. in colorectal ...

  3. Causes of cancer - Wikipedia

    en.wikipedia.org/wiki/Causes_of_cancer

    The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [1] [2] A minority of cancers are due to inherited genetic mutations. [3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [4] Cancer is generally not contagious in humans, though it can be caused by oncoviruses and cancer ...

  4. Carcinogenesis - Wikipedia

    en.wikipedia.org/wiki/Carcinogenesis

    Cancers and tumors are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat. Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.

  5. Mutagenesis - Wikipedia

    en.wikipedia.org/wiki/Mutagenesis

    DNA may be modified, either naturally or artificially, by a number of physical, chemical and biological agents, resulting in mutations. Hermann Muller found that "high temperatures" have the ability to mutate genes in the early 1920s, [2] and in 1927, demonstrated a causal link to mutation upon experimenting with an x-ray machine, noting phylogenetic changes when irradiating fruit flies with ...

  6. Two thirds of cancers caused by random genetic mistakes ... - AOL

    www.aol.com/news/2017-03-23-two-thirds-of...

    Although most of these mutations cannot be prevented, the team stressed that early detection and treatment can prevent many cancer deaths, regardless of the cause. Though most cancers are due to ...

  7. DNA repair - Wikipedia

    en.wikipedia.org/wiki/DNA_repair

    Deficient expression of DNA repair proteins due to an inherited mutation can cause increased risk of cancer. Individuals with an inherited impairment in any of 34 DNA repair genes (see article DNA repair-deficiency disorder) have an increased risk of cancer, with some defects causing up to a 100% lifetime chance of cancer (e.g. p53 mutations ...

  8. No, cooking oil doesn't cause cancer — but new study links ...

    www.aol.com/no-cooking-oil-doesnt-cause...

    The study, conducted in a lab funded by the National Cancer Institute, focused on the role of lipids, also known as fats, in the microenvironments around colon cancer tumors.

  9. Mutational signatures - Wikipedia

    en.wikipedia.org/wiki/Mutational_signatures

    Ultraviolet radiation: UVB radiation causes direct DNA damage and is a known risk factor for skin cancer (e.g. melanoma) Alkylating antineoplastic agents: This group of chemotherapy agents adds alkyl group to DNA, which causes crosslinking of DNA and interferes with DNA replication and DNA repair.